The Syntopix business is based upon world-class research in the fields of skin microbiology, antibiotic resistance in skin bacteria and Staphylococcus aureus as well as the pathobiology of acne and eczema. Publications of this research include:
Temporal changes in sebum excretion and propionibacterial
colonization in preadolescent children with and without acne.
Mourelatos K, Eady EA, Cunliffe WJ, Clark SM, Cove JH.
Br J Dermatol. 2007 Jan;156(1):22-31.
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Efficacy of oral isotretinoin in the control of skin and nasal
colonization by antibiotic-resistant propionibacteria in patients with
acne.
Coates P, Vyakrnam S, Ravenscroft JC, Stables GI, Cunliffe WJ, Leyden
JJ, Johnson J, Eady EA, Cove JH.
Br J Dermatol. 2005 Dec;153(6):1126-36. Erratum in: Br J Dermatol.
2006 Apr;154(4):807.
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ABC proteins and antibiotic drug resistance: is it all about
transport?
Kerr ID, Reynolds ED, Cove JH.
Biochem Soc Trans. 2005 Nov;33 (Pt 5):1000-2.
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Enhanced resistance to erythromycin is conferred by the
enterococcal msrC determinant in Staphylococcus aureus.
Reynolds E, Cove JH.
J Antimicrob Chemother. 2005 Feb;55(2):260-4. Epub 2005 Jan. 13
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Comparison of five antimicrobial regimens for treatment of mild to
moderate inflammatory facial acne vulgaris in the community:
randomised controlled trial
Ozolins M, Eady EA, Avery AJ, Cunliffe WJ, Po AL, O'Neill C, Simpson
NB, Walters CE, Carnegie E, Lewis JB, Dada J, Haynes M, Williams K,
Williams HC.
Lancet. 2004 Dec 18-31;364(9452):2188-95.
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Short-term effects of topical fusidic acid or mupirocin on the
prevalence of fusidic acid resistant (FusR) Staphylococcus aureus in atopic eczema.
Ravenscroft JC, Layton AM, Eady EA, Murtagh MS, Coates P, Walker
M, Cove JH.
Br J Dermatol. 2003 May;148(5):1010-7.
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Msr(A) and related macrolide/streptogramin resistance determinants:
incomplete transporters?
Reynolds E, Ross JI, Cove JH.
Int J Antimicrob Agents. 2003 Sep;22(3):228-36.
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Correlation between enterococcal biofilm formation in vitro and
medical-device-related infection potential in vivo.
Sandoe JA, Witherden IR, Cove JH, Heritage J, Wilcox MH.
J Med Microbiol. 2003 Jul;52(Pt 7):547-50.
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Cytolysin gene expression in Enterococcus faecalis is regulated
in response to aerobiosis conditions.
Day AM, Cove JH, Phillips-Jones MK.
Mol Genet Genomics. 2003 Apr;269(1):31-9.
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06/08/2008 13:13
Syntopix proposal to raise £1.5million passed by shareholders...
03/07/2008 07:00
Syntopix enters into joint development agreement with Procter & Gamble...
25/02/2008 07:00
Syntopix announces positive results from its Phase II cosmetic study...